drug use

His films like 'Requiem for a Dream' and 'The Wrestler' unflinchingly explore addiction's psychological and physical devastation through visceral, immersive filmmaking.

He examines drug use and its social consequences across multiple works including 'Drugstore Cowboy' and 'My Own Private Idaho,' often centering marginalized communities.

His landmark film 'Trainspotting' revolutionized cinema's portrayal of heroin addiction, blending dark humor, style, and brutal realism to capture the cycle of dependency.