drugs

His films like 'Requiem for a Dream' and 'The Fountain' unflinchingly depict addiction's psychological and physical devastation through visceral visual storytelling.

He explores drug culture and addiction with nuanced empathy in films like 'Drugstore Cowboy' and 'My Own Private Idaho,' capturing the lived experience of users.

His kinetic direction in 'Trainspotting' revolutionized how cinema portrays heroin addiction, blending style with raw social commentary on drug epidemics.