heroin

His film 'Requiem for a Dream' is a visceral, unflinching exploration of addiction in all its forms, with heroin addiction as a central narrative thread depicting psychological and physical devastation.

Van Sant's 'Drugstore Cowboy' and 'My Own Private Idaho' authentically portray the lives of heroin addicts and street hustlers with empathy and unflinching realism.

His film 'Trainspotting' presents a raw, darkly comedic yet devastating portrait of heroin addiction in Edinburgh, capturing both the seductive allure and brutal consequences of the drug.