heroin

His film 'Requiem for a Dream' is a visceral, unflinching exploration of addiction's devastating psychological and physical toll across multiple characters.

He examined heroin addiction and urban decay through intimate character studies in films like 'Drugstore Cowboy' and 'My Own Private Idaho.'

His film 'Trainspotting' became a cultural landmark for its raw, energetic portrayal of heroin addiction in 1990s Edinburgh with unforgettable visual style.